| Identification | Back Directory | [Name]
Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 | [CAS]
1926163-82-7 | [Synonyms]
Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 | [Molecular Formula]
C66H82N16O17S | [MDL Number]
MFCD18782563 | [MOL File]
1926163-82-7.mol | [Molecular Weight]
1403.52 |
| Chemical Properties | Back Directory | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Formic Acid: 1 mg/ml | [form ]
A lyophilized powder | [pka]
12.98±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14).1 Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.
| [storage]
Store at -20°C | [References]
1. Eckhouse, S.R., Akerman, A.W., Logdon, C.B., et al. Differential membrane type 1 matrix metalloproteinase substrate processing with ischemia-reperfusion: Relationship to interstitial microRNA dynamics and myocardial function J. Thorac. Cardiovasc. Surg. 145(1),267-275(2013). |
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