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ChemicalBook--->CAS DataBase List--->186185-03-5

186185-03-5

186185-03-5 Structure

186185-03-5 Structure
IdentificationBack Directory
[Name]

1,4-Dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-pyridinedicarboxylicacid3,5-dimethylesterL-Lactate
[CAS]

186185-03-5
[Synonyms]

BMS 193885
BMS-193885 >=98% (HPLC)
1,4-dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-dimethyl ester-3,5-pyridinedicarboxylic acid
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-, 3,5-dimethyl ester
1,4-Dihydro-4-[3-[[[[3-[4-(3-methoxyphenyl)-1-piperidinyl]propyl]amino]carbonyl]amino]phenyl]-2,6-dimethyl-3,5-pyridinedicarboxylicacid3,5-dimethylesterL-Lactate
[Molecular Formula]

C33H42N4O6
[MDL Number]

MFCD16878998
[MOL File]

186185-03-5.mol
[Molecular Weight]

590.71
Chemical PropertiesBack Directory
[Boiling point ]

707.5±60.0 °C(Predicted)
[density ]

1.188±0.06 g/cm3(Predicted)
[storage temp. ]

Desiccate at +4°C
[solubility ]

DMSO: >10mg/mL
[form ]

powder
[pka]

13.94±0.46(Predicted)
[color ]

light yellow to yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
[Hazard Codes ]

Xn
[Risk Statements ]

22
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

BMS 193885, is a potent, and competitive neuropeptide (NPY) Y1 antagonist, that has also displayed 160-fold selectivity over σ1, α1, Y2, Y4 and Y5 receptors respectively. BMS 193885, is also brain penetrant, and able to reduce food intake and body weight through central Y1 inhibition.
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