Identification | Back Directory | [Name]
BENZOIC ACID, 3-FLUORO-4-[[(2R)-HYDROXY(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHALENYL)ACETYL]AMINO]- | [CAS]
185629-22-5 | [Synonyms]
BMS 961 BMS 189961 BMS 187948 BMS 270394 (R)-3-Fluoro-4-(2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)acetamido)b 3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID 3-Fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-2-naphthalenyl)acetyl]amino]-benzoic acid Benzoic acid, 3-fluoro-4-[[2-hydroxy-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)acetyl]amino]- BENZOIC ACID, 3-FLUORO-4-[[(2R)-HYDROXY(5,6,7,8-TETRAHYDRO-5,5,8,8-TETRAMETHYL-2-NAPHTHALENYL)ACETYL]AMINO]- 3-FLUORO-4-[(R)-2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID | [Molecular Formula]
C23H26FNO4 | [MDL Number]
MFCD10565938 | [MOL File]
185629-22-5.mol | [Molecular Weight]
399.46 |
Chemical Properties | Back Directory | [Boiling point ]
590.9±50.0 °C(Predicted) | [density ]
1.241±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: soluble | [form ]
A crystalline solid | [pka]
3.92±0.10(Predicted) |
Hazard Information | Back Directory | [Uses]
BMS961 is a potent and selective retinoic acid receptor gamma (RARγ) agonist with IC50 values of 30 nM. RARγ belongs to the family of nuclear receptors which regulates transcription. in vitro, application of BMS961on mouse ear skin was found to cause a significant increase of thymic stromal lymphopoietin (TSLP) transcripts1. | [storage]
Store at +4°C |
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