| Identification | Back Directory | [Name]
NITROFEN | [CAS]
1836-75-5 | [Synonyms]
TOK
NIP
toke
tok-2
fw925
FW 925
toke40
TOK(R)
NIP(R)
tokkorn
toke-25
mezotox
nitofen
nitrafen
TOK E 25
tokwp-50
trizilin
NICLOFEN
Nitrofcn
NITROFEN
Nithophen
FW-925(R)
Nitrophen
Nitraphen
nitrofene
nci-c00420
Nitrochlor
Nitrophene
trizilin25
NICLOFEN(R)
preparation125
Nitrofen, >=97%
nitrofene(french)
NIP、TOK、WP-50、FW-925
NITROFEN, 100MG, NEAT
NITROFEN PESTANAL
nitrofen (bsi,iso,wssa)
TOKUNAGA human cell line
Nitrofen solution,100ppm
Nitrofen 100mg [1836-75-5]
2,4-Dichloro-1-(4-nitrophenoxy)
2,4-dichloro-4’-nitrophenylether
4-nitro-2’,4’-dichlorophenylether
4’-nitro-2,4-dichlorodiphenylether
2’,4’-dichloro-4-nitrobiphenylether
2,4-Dichloro-4'-nitrodiphenyl ether
4-(2,4-DICHLOROPHENOXY)NITROBENZENE
2,4-dechlorophenylp-nitrophenylether
2,4-dichlorophenyl4-nitrophenylether
2,4-dichlorophenylp-nitrophenylether
2,4-dichlorphenyl-4-nitrophenylaether
2,4-dichloro-(4-nitrophenoxy)-Benzene
ether,2,4-dichlorophenylp-nitrophenyl
4-(2,4-Dichlorophenoxy)nitrobenzenene
2,4-DICHLORO-1-(4-NITROPHENOXY)BENZENE
Benzene,2,4-dichloro-(4-nitrophenoxy)-
2,4-dichloro-1-(4-nitrophenoxy)-benzen
2,4-Dichlorophenyl 4-nitrophenyl ether
2,4-Dichlorophenyl p-nitrophenyl ether
2,4-Dichlorophenyl-4’-nitrophenylether
Ether, 2,4-dichlorophenyl p-nitrophenyl
2,4-DICHLOROPHENYLPARA-NITROPHENYLETHER
NITROFEN PESTANAL (2,4-DICHLORO- PHENYL-
benzene,2,4-dichloro-1-(4-nitrophenoxy)-
Benzene, 2,4-dichloro-1-(4-nitrophenoxy)-
nitrofen (ISO) 2,4-dichlorophenyl 4-nitrophenyl ether | [EINECS(EC#)]
217-406-0 | [Molecular Formula]
C12H7Cl2NO3 | [MDL Number]
MFCD00128026 | [MOL File]
1836-75-5.mol | [Molecular Weight]
284.09 |
| Chemical Properties | Back Directory | [Appearance]
solid | [Melting point ]
69-70°C | [Boiling point ]
368 ºC | [density ]
1.3 | [refractive index ]
1.6140 (estimate) | [Fp ]
205℃ | [storage temp. ]
0-6°C | [solubility ]
soluble in Methanol | [form ]
Solid | [color ]
White to Light yellow | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Water Solubility ]
1mg/L(22 ºC) | [Merck ]
14,6598 | [BRN ]
1887356 | [IARC]
2B (Vol. 30, Sup 7) 1987 | [NIST Chemistry Reference]
| [EPA Substance Registry System]
Benzene, 2,4-dichloro-1-(4-nitrophenoxy)- (1836-75-5) |
| Hazard Information | Back Directory | [Chemical Properties]
solid | [Uses]
Formerly as herbicide. | [General Description]
Colorless crystals or black solid. Used as a pre- or post-emergence herbicide. | [Air & Water Reactions]
Insoluble in water. | [Reactivity Profile]
NITROFEN is a nitrated and halogenated ether derivative. | [Fire Hazard]
Flash point data for NITROFEN are not available; however, NITROFEN is probably combustible. | [Potential Exposure]
Nitrofen is a contact herbicide used
for pre-and post-emergency control of annual grasses and
broadleaf weeds on a variety of food and ornamental crops.
Occupational exposure to nitrofen, primarily through
inhalation and dermal contact may occur among workers
at production facilities. Field handlers of the herbicide
are subject to inhalation exposure during application
procedures. | [First aid]
Skin Contact: Flood all areas of body that have
contacted the substance with water. Don’t wait to remove
contaminated clothing; do it under the water stream. Use
soap to help assure removal. Isolate contaminated clothing
when removed to prevent contact by others. Eye
Contact: Remove any contact lenses at once. Immediately
flush eyes well with copious quantities of water or normal
saline for at least 20 30 minutes. Seek medical attention.
Inhalation: Leave contaminated area immediately; breathe
fresh air. Proper respiratory protection must be supplied to
any rescuers. If coughing, difficult breathing or any other
symptoms develop, seek medical attention at once, even if
symptoms develop many hours after exposure. Ingestion:
Contact a physician, hospital or poison center at once. If
the victim is unconscious or convulsing, do not induce
vomiting or give anything by mouth. Assure that the
patient’s airway is open and lay him on his side with his
head lower that his body and transport immediately to a
medical facility. If conscious and not convulsing, give a
glass of water to dilute the substance. Vomiting should not
be induced without a physician’s advice. | [Shipping]
UN3345 Phenoxyacetic acid derivative pesticide,
solid, toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
UN3077 Environmentally hazardous substances, solid,
n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous
material, Technical Name Required. | [Waste Disposal]
Small quantities may be landfilled
but large quantities should be incinerated. In
accordance with 40CFR165, follow recommendations for
the disposal of pesticides and pesticide containers. Must be
disposed properly by following package label directions or
by contacting your local or federal environmental control
agency, or by contacting your regional EPA office. | [Definition]
ChEBI: Nitrofen is an organic molecular entity. It has a role as an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor and a herbicide. | [Health Hazard]
Nitrofen is moderately toxic by ingestionand inhalation of dusts. The lethal doses in cats from oral administration and inhalationof dusts are 300 mg/kg and 620 mg/m3/4h,respectively (NIOSH 1986). Bovine calvestreatedorally by 1.5 mL 25% nitrofen/kg produced toxic effects after 36–48 hours. Thesymptoms were increase in body temperature, depression, and progressive decrease inrespiration rate and pulse rate,similar to tribulin (Gupta and Singh 1985). An increase inthe activities of serum glutamic-oxaloacetictransaminase and glutamipyruvictransaminase was noted(Gupta and Singh 1984). Nitrofen has beenfound to cause cancer in animals. There issufficient evidence of its carcinogenicity inanimals (IARC). Oral administration in micecaused liver and lung cancers. | [Carcinogenicity]
Nitrofen is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. |
| Safety Data | Back Directory | [Hazard Codes ]
T,N | [Risk Statements ]
45-61-50/53-22 | [Safety Statements ]
45-53-61-60-50/53-22 | [RIDADR ]
3077 | [WGK Germany ]
3 | [RTECS ]
KN8400000 | [TSCA ]
Yes | [HazardClass ]
9 | [PackingGroup ]
III | [HS Code ]
29093090 | [Safety Profile]
Confirmed carcinogen
with experimental carcinogenic data. Poison
by ingestion. Moderately toxic by inhalation
and possibly other routes. Experimental
teratogenic and reproductive effects. A skin
and severe eye irritant. Mutation data
reported. A broad-spectrum herbicide. See
also NITRO COMPOUNDS of
AROMATIC HYDROCARBONS and
ETHERS. When heated to decomposition it
emits very toxic fumes of Cl and NOx. | [Hazardous Substances Data]
1836-75-5(Hazardous Substances Data) | [Toxicity]
LD50 orally in rats: 3.58 g/kg (Ambrose) |
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