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ChemicalBook--->CAS DataBase List--->1832576-25-6

1832576-25-6

1832576-25-6 Structure

1832576-25-6 Structure
IdentificationBack Directory
[Name]

Urea, N-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-N'-[5-chloro-6-(2H-1,2,3-triazol-2-yl)-3-pyridinyl]-
[CAS]

1832576-25-6
[Synonyms]

MLT-985
Urea, N-[2-chloro-7-[(1S)-1-methoxyethyl]pyrazolo[1,5-a]pyrimidin-6-yl]-N'-[5-chloro-6-(2H-1,2,3-triazol-2-yl)-3-pyridinyl]-
[Molecular Formula]

C17H15Cl2N9O2
[MOL File]

1832576-25-6.mol
[Molecular Weight]

448.27
Chemical PropertiesBack Directory
[density ]

1.67±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[form ]

Solid
[pka]

7.98±0.46(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 value of 3 nM.
[References]

[1]. Quancard J, et al. Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood. J Med Chem. 2020 Dec 10;63(23):14594-14608.
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