| Identification | Back Directory | [Name]
4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylic acid | [CAS]
182808-04-4 | [Synonyms]
Prucalopride Impurity 35
7-Benzofurancarboxylic acid, 4-amino-5-chloro-2,3-dihydro-, methyl ester
Prucalopride impurity D
Methyl 4-amino-5chloro-2,3dihydrobenzofuran7-carboxylate
Prucalopride Impurity 9/methyl 4-amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylate | [Molecular Formula]
C10H10ClNO3 | [MOL File]
182808-04-4.mol | [Molecular Weight]
227.64 |
| Chemical Properties | Back Directory | [Boiling point ]
425.1±45.0 °C(Predicted) | [density ]
1.407±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
-0.13±0.20(Predicted) |
| Hazard Information | Back Directory | [Uses]
Methyl 4-Amino-5-chloro-2,3-dihydrobenzofuran-7-carboxylate is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe. In addition, it is an intermediate in the preparation of enterokinetic agent R108512. |
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| Company Name: |
TOSUN PHARM
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020-61855200 13326451905 |
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www.toref.cn/ |
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