| Identification | Back Directory | [Name]
1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine | [CAS]
180300-43-0 | [Synonyms]
ECyd
TAS 106
ETHYNYCYTIDINE
Ethynylcytidine
3'-Ethynylcytidine
3'-C-Ethynylcytidine
3’-β-C-Ethynylcytidine
cytidine, 3'-c-ethynyl-
Ethynylcytidine (TAS-106)
3'-beta-C-Ethynylcytidine
ECYD;TAS-106;3'-C-ETHYNYLCYTIDINE
3’-beta-C-Ethynylcytidine, ECYD, TAS-106
1-(3-C-ethynyl-β-D-ribo-pentofuranosyl)cytosine
1-(3-C-ETHYNYL-BETA-D-RIBO-PENTOFURANOSYL)CYTOSINE
4-Amino-1-((2R,3R,4S,5R)-4-ethynyl-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one | [Molecular Formula]
C11H13N3O5 | [MOL File]
180300-43-0.mol | [Molecular Weight]
267.24 |
| Chemical Properties | Back Directory | [Melting point ]
233-235 °C | [Boiling point ]
536.4±60.0 °C(Predicted) | [density ]
1.61±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:127.5(Max Conc. mg/mL);477.1(Max Conc. mM)
DMF:5.0(Max Conc. mg/mL);18.71(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);37.42(Max Conc. mM) | [form ]
A solid | [pka]
11.54±0.70(Predicted) | [color ]
White to yellow |
| Hazard Information | Back Directory | [Uses]
Ethynylcytidine, is a new nucleoside antimetabolite, and an RNA polymerase inhibitor, combined with cisplatin exhibits a potent synergistic growth-inhibitory effect via Vaults dysfunction | [storage]
Store at -20°C |
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