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ChemicalBook--->CAS DataBase List--->1798787-27-5

1798787-27-5

1798787-27-5 Structure

1798787-27-5 Structure
IdentificationBack Directory
[Name]

BIIB068
[CAS]

1798787-27-5
[Synonyms]

BIIB068
BIIB-068
N-[(2-methyl-4-{2-[(1-methyl-1H-pyrazol-4-yl)amino]pyrimidin-4-yl}phenyl)methyl]-3-(propan-2-yloxy)azetidine-1-carboxamide
1-Azetidinecarboxamide, 3-(1-methylethoxy)-N-[[2-methyl-4-[2-[(1-methyl-1H-pyrazol-4-yl)amino]-4-pyrimidinyl]phenyl]methyl]-
ADME,inhibit,FcγR,Autoimmune,Bruton tyrosine kinase,TNFα,BIIB 068,ROS,Inhibitor,reversible,Btk,anti-IgD,phosphorylation,BIIB068,anti-IgM,BIIB-068
[Molecular Formula]

C23H29N7O2
[MOL File]

1798787-27-5.mol
[Molecular Weight]

435.52
Chemical PropertiesBack Directory
[density ]

1.30±0.1 g/cm3(Predicted)
[solubility ]

DMSO:30.63(Max Conc. mg/mL);70.33(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.46(Max Conc. mM)
DMF:30.0(Max Conc. mg/mL);68.88(Max Conc. mM)
Ethanol:10.0(Max Conc. mg/mL);22.96(Max Conc. mM)
[form ]

A crystalline solid
[pka]

13.40±0.40(Predicted)
[color ]

Off-white to yellow
Spectrum DetailBack Directory
[Spectrum Detail]

BIIB068(1798787-27-5)1HNMR
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