Identification | Back Directory | [Name]
Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide | [CAS]
179420-17-8 | [Synonyms]
CJ-13610 CJ-13610
(CJ13610) CJ-13610 >=98% (HPLC) Tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-2H-pyran-4-carboxamide 2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]- 4-(3-((4-(2-METHYL-1H-IMIDAZOL-1-YL)PHENYL)SULFANYL)PHENYL)TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE Lipoxygenase,inhibit,CJ 13,610,LOX,nonredox-type,polymorphonuclear leukocytes,Inhibitor,CJ-13,610,arachidonic acid,CJ13,610 | [Molecular Formula]
C22H23N3O2S | [MDL Number]
MFCD00948114 | [MOL File]
179420-17-8.mol | [Molecular Weight]
393.5 |
Hazard Information | Back Directory | [Uses]
CJ-13610 may be used to study 5-lipoxygenase-mediated cell signaling. | [Biochem/physiol Actions]
CJ-13610 inhibits the biosynthesis of leukotriene B4 and regulates the IL-6 mRNA expression in macrophages. It reduces fibrosis and necroinflammation of liver in carbon tetrachloride-treated mice. | [storage]
Store at -20°C |
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