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ChemicalBook--->CAS DataBase List--->17680-84-1

17680-84-1

17680-84-1 Structure

17680-84-1 Structure
IdentificationBack Directory
[Name]

HOMOPLANTAGININ
[CAS]

17680-84-1
[Synonyms]

Hispiduloside
HOMOPLANTAGININ
Homoplantaginin, >99%
Hispidulin 7-glucoside
HOMOPLANTAGININ USP/EP/BP
Homoplantaginin >=98% (HPLC)
4H-1-Benzopyran-4-one,7-(b-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-
4H-1-Benzopyran-4-one, 7-(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-
7-(beta-D-Glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-Benzopyran-4-one
5-hydroxy-2-(4-hydroxyphenyl)-6-methoxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one
[Molecular Formula]

C22H22O11
[MDL Number]

MFCD04039835
[MOL File]

17680-84-1.mol
[Molecular Weight]

462.4
Chemical PropertiesBack Directory
[Melting point ]

256-258℃
[Boiling point ]

798.1±60.0 °C(Predicted)
[density ]

1.609
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 25mg/mL; DMSO: 20mg/mL
[form ]

A solid
[pka]

6.11±0.40(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Chemical Properties]

Homoplantaginin belong to flavonoids, easily soluble in methanol and ethanol, slightly soluble in acetone, and insoluble in water. Its hemihydrate is a yellow crystal.
[Uses]

Homoplantaginin has bacteriostatic effect. It has moderate inhibitory effect on the common pathogenic bacteria of chronic bronchitis such as Staphylococcus albus and pneumococcus in vitro. It has a certain antagonistic effect on the infection of Staphylococcus aureus in animals, and can reduce the mortality rate 20 %. It has certain antitussive and expectorant effects, and its expectorant ability is greater than that of ammonium chloride. It can be used to treat chronic bronchitis with less toxicity.
[Definition]

ChEBI: Homoplantaginin is a glycoside and a member of flavonoids.
[Synthesis]

Extraction process of Homoplantaginin in lychee grass: lychee grass decoction pieces--crushing--solvent extraction--filtration and decompression concentration--extraction--dehydration--suction filtration silica gel column separation--purification (recrystallization)--suction filtration-- dry.
[storage]

Store at -20°C
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