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ChemicalBook--->CAS DataBase List--->175140-00-8

175140-00-8

175140-00-8 Structure

175140-00-8 Structure
IdentificationBack Directory
[Name]

CP 376395
[CAS]

175140-00-8
[Synonyms]

CP 376395
CP 376395 hydrochloride
CP376395;CP-376395;CP 376395
4-Pyridinamine, N-(1-ethylpropyl)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-
N-(1-Ethylpropyl)-3,6-dimethyl-2-(2,4,6-trimethylphenoxy)-4-pyridinaminehydrochloride
[Molecular Formula]

C21H30N2O
[MDL Number]

MFCD11519966
[MOL File]

175140-00-8.mol
[Molecular Weight]

326.48
Chemical PropertiesBack Directory
[Melting point ]

224 °C
[Boiling point ]

434.9±45.0 °C(Predicted)
[density ]

1.018±0.06 g/cm3(Predicted)
[storage temp. ]

Desiccate at RT
[solubility ]

DMF: 30 mg/ml; DMSO: 15 mg/ml; Ethanol: 30 mg/ml
[form ]

A crystalline solid
[pka]

7.23±0.48(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

Potent and selective CRF 1 receptor antagonist (K i values are 12 and >10000 nM for CRF 1 and CRF 2 receptors respectively). Attenuates CRF-induced activation of the HPA axis in vivo following i.v. administration. Orally active.
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