| Identification | Back Directory | [Name]
5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole | [CAS]
174672-06-1 | [Synonyms]
AN-2718
5-Chloro-2,1-benzoxaborol-1(3H)-ol
5-chlorobenzo[c][1,2]oxaborol-1(3H)-ol
5-Chloro-1,3-dihydro-2,1-benzoxaborol-1-ol, 95%
5-Chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole
2,1-Benzoxaborole, 5-chloro-1,3-dihydro-1-hydroxy- | [Molecular Formula]
C7H6BClO2 | [MDL Number]
MFCD18633195 | [MOL File]
174672-06-1.mol | [Molecular Weight]
168.39 |
| Chemical Properties | Back Directory | [Melting point ]
150-154 °C | [Boiling point ]
273.2±50.0 °C(Predicted) | [density ]
1.35±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 30 mg/mL; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/mL | [form ]
A crystalline solid | [pka]
6.60±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Biological Activity]
AN-2718 inhibits the growth of fungi by inhibiting protein synthesis through the OBORT mechanism. | [in vitro]
AN2718 inhibits cytoplasmic LeuRS from molds, A. fumigatus , and from yeasts, C. albicans , with an IC 50 of 2 μM and 4.2 μM, respectively. AN2718 has good MIC90 activity against the dermatophytes, T. rubrum and T. mentagrophytes . | [target]
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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