| Identification | Back Directory | [Name]
S-3013 | [CAS]
172733-08-3 | [Synonyms]
A-002
S-3013
Varespladib Methyl
Acetic acid, 2-[[3-(2-amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]-, methyl ester | [Molecular Formula]
C22H22N2O5 | [MDL Number]
MFCD09833542 | [MOL File]
172733-08-3.mol | [Molecular Weight]
394.42 |
| Chemical Properties | Back Directory | [Melting point ]
172-187 °C | [Boiling point ]
624.6±65.0 °C(Predicted) | [density ]
1.26±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 100 mg/mL (253.54 mM) | [form ]
Solid | [pka]
12?+-.0.50(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Definition]
ChEBI: Varespladib methyl is a methyl ester resulting from the formal condensation of the carboxy group of varespladib with methanol. It is a potential therapy for the treatment of snakebite envenomings in which toxicity depends on the action of PLA2s. It has a role as a prodrug, an anti-inflammatory drug, an antidote and an EC 3.1.1.4 (phospholipase A2) inhibitor. It is a methyl ester, an aromatic ether, a member of benzenes, a member of indoles and a primary carboxamide. It is functionally related to a varespladib. |
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SPIRO PHARMA
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www.spiropharma.com.cn |
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InvivoChem
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13549236410 |
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MedChemExpress
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www.medchemexpress.com |
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