Identification | Back Directory | [Name]
1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride | [CAS]
16899-81-3 | [Synonyms]
U 12844A Isoprenaline impurity A Norepinephrine Impurity 10 Isoprenaline EP Impurity A Isoprenaline impurity A CRS Isoprenaline EP Impurity A HCl Isoprenaline HCl EP Impurity A HCl Isoprenaline hydrochloride EP Impurity A 3',4'-DIHYDROXY-2-(ISOPROPYLAMINO)-ACETOPHENONE HYDROCHLORIDE 1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino] hydrochloride [2-(3,4-DIHYDROXYPHENYL)-2-OXOETHYL]-PROPAN-2-YLAZANIUM,CHLORIDE 1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]ethanone hydrochloride Ethanone,1-(3,4-dihydroxyphenyl)-2-[(1-methylethyl)amino]-, hydrochloride (1:1) | [EINECS(EC#)]
240-943-7 | [Molecular Formula]
C11H15NO3.ClH | [MDL Number]
MFCD00035076 | [MOL File]
16899-81-3.mol | [Molecular Weight]
245.704 |
Hazard Information | Back Directory | [Uses]
1-(3,4-Dihydroxyphenyl)-2-[(1-methylethyl)amino]-ethanone is an impurity of Isoprenaline (I874200, HCl salt) which is non-selective beta-adrenergic agonist. Isoprenaline is used in the treatment of bradycardia. | [Preparation]
Obtained by condensation of a-chloro-3,4- dihydroxy-acetophenone with isopropylamine in isopropanol at 65–70°. The amino ketone which separated was treated with concentrated hydrochloric acid (54%), (46%). |
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