Identification | Back Directory | [Name]
Sitagliptin IMpurity | [CAS]
1675201-14-5 | [Synonyms]
Sitagliptin-4 Impurity FP-C Sitagliptin IMpurity Sitagliptin Impurity FP-C (E)-1-(3-(trifluoromethyl) Sitagliptin Styrylacetyl Analog 3-Desamino-3,4-dehydro Sitagliptin Sitagliptin Styrylacetyl Analog Impurity Sitagliptin Impurity 68(Mixture of Z and E Isomers) (R)-2-((tert-butoxycarbonyl)amino)-3-(2,4,5-trifluorophenyl)propyl 4-methylbenzenesulfonate 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-3-buten-1-one 3-Buten-1-one, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)- Sitagliptin impurity 38/(E)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a] pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-3-en-1-one | [Molecular Formula]
C16H12F6N4O | [MOL File]
1675201-14-5.mol | [Molecular Weight]
390.28 |
Chemical Properties | Back Directory | [Melting point ]
113-115°C | [Boiling point ]
504.1±60.0 °C(Predicted) | [density ]
1.52±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
-0.03±0.20(Predicted) | [color ]
White to Off-White |
Hazard Information | Back Directory | [Uses]
1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-3-buten-1-one is a derivative of Sitagliptin(S491000) which is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes. |
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