| Identification | Back Directory | [Name]
TAPI-1 | [CAS]
163847-77-6 | [Synonyms]
TAPI-1
(2R)-TAPI-1
TAPI-1 acetate salt
TNF-ALPHA PROTEASE INHIBITOR-1
HONHCOCH2CH(CH2-CH(CH3)2)CO-NAL-ALA-NHCH2CH2NH2
N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)--alanyl-L-alaninamide
N-(R)-[2-(HYDROXYAMINOCARBONYL)METHYL]-4-METHYLPENTANOYL-L-NAPHTHYLALANYL-L-ALANINE, 2-AMINOETHYL AMIDE
N-(R)-(2-(HYDROXYAMINOCARBONYL)METHYL)-4-METHYLPENTANOYL-L-3-(2'-NAPHTHYL)ALANYL-L-ALANINE 2-AMINOETHYL AMIDE
L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-
N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-N-(2-aminoethyl)-L-Alaninamide acetate salt | [Molecular Formula]
C26H37N5O5 | [MDL Number]
MFCD02684280 | [MOL File]
163847-77-6.mol | [Molecular Weight]
499.6 |
| Chemical Properties | Back Directory | [density ]
1?+-.0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [form ]
powder | [pka]
9.17±0.20(Predicted) | [color ]
white to beige |
| Hazard Information | Back Directory | [Uses]
TAPI-1 acetate salt has been used as a tumor necrosis factor(TNF)-α convertase/ADAM17/α-secretase (TACE) inhibitor. | [Biochem/physiol Actions]
TAPI-1 is a potent inhibitor of matrix metalloproteinases and TACE (TNF-α convertase/ADAM17/α-secretase). | [storage]
Store at -20°C |
|
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Sigma-Aldrich
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Musechem
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www.musechem.com |
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