| Identification | Back Directory | [Name]
ETPI HCL | [CAS]
163490-78-6 | [Synonyms]
EPIT HCL
ETPI HCL
TFPI HCL
SEPIT HCL
TFPI hydrochloride
ETPI, HYDROCHLORIDE
S-ETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]-ISOTHIOUREA, HCL
S-EthylN-[4-Triflurormethyl)phenyl]isothiourea,hydrochloride
S-ETHYL-N-[4-(TRIFLUOROMETHYL)PHENYL]ISOTHIOUREA HYDROCHLORIDE
S-ETHYL N-[4-(TRIFLUORORMETHYL)PHENYL]ISOTHIOUREA, HYDROCHLORIDE
ETHYL[4-(TRIFLUOROMETHYL)PHENYL] CARBAMIMIDOTHIOATE, HYDROCHLORIDE
S-Ethyl-N-[4-(trifluoromethyl)phenyl]-isothiourea hydrochloride,98% | [Molecular Formula]
C10H12ClF3N2S | [MDL Number]
MFCD01320531 | [MOL File]
163490-78-6.mol | [Molecular Weight]
284.73 |
| Chemical Properties | Back Directory | [Appearance]
white to off-white solid | [Melting point ]
143-147 °C
| [storage temp. ]
0-6°C | [solubility ]
DMF: >54 mg/ml; DMSO: >33.6 mg/ml; Ethanol: >55 mg/ml; Ethanol:PBS (pH 7.2) 1:3: 1 mg/ml; PBS pH 7.2: <50 μg/ml; Water: 50 mg/ml | [form ]
White to off-white solid. | [CAS DataBase Reference]
163490-78-6 |
| Hazard Information | Back Directory | [Chemical Properties]
white to off-white solid | [Uses]
A selective inhibitor of nNOS (NOS I) relative to iNOS (NOS II) (115-fold) and eNOS (NOS III) (29-fold). It also binds competitively with L-Arginine | [Uses]
EPIT is a selective, competitive inhibitor of nNOS having a Ki of 0.32 μM for the purified human enzyme. EPIT exhibits 115-fold and 29-fold selectivity for nNOS compared to iNOS and eNOS, respectively. It exhibits reduced inhibitory potency in whole-cell assays, possibly due to reduced intracellular uptake. | [storage]
Store at -20°C |
|
| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Boao Pike
|
| Tel: |
010-57798038 15652371397 |
| Website: |
www.biopike.cn |
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