| Identification | Back Directory | [Name]
3-Pyridinecarboxylic acid, 2-[(4-chlorophenyl)amino]- | [CAS]
16344-26-6 | [Synonyms]
2-[(4-Chlorophenyl)amino]-3-pyridinecarboxylic acid
2-[(4-chlorophenyl)amino]-3-Pyridine carbocylic acid
3-Pyridinecarboxylic acid, 2-[(4-chlorophenyl)amino]- | [Molecular Formula]
C12H9ClN2O2 | [MDL Number]
MFCD03114306 | [MOL File]
16344-26-6.mol | [Molecular Weight]
248.67 |
| Chemical Properties | Back Directory | [Melting point ]
209-211 °C(Solv: ethanol (64-17-5)) | [Boiling point ]
413.4±40.0 °C(Predicted) | [density ]
1.435±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (402.14 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [pka]
1.70±0.36(Predicted) | [color ]
Off-white to gray |
| Hazard Information | Back Directory | [Biological Activity]
DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor (IC50=0.40 μM). DHODH-IN-17 can be used for theresearch of acute myeloid leukemia (AML)[1].
DHODH-IN-17, a 2-anilino nicotinic acid, is a human DHODH inhibitor with an IC50 value of 0.40 μM[1]. | [References]
[1]. Lewis TA, et al. Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. ACS Med Chem Lett. 2016;7(12):1112-1117. |
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