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ChemicalBook--->CAS DataBase List--->1628530-37-9

1628530-37-9

1628530-37-9 Structure

1628530-37-9 Structure
IdentificationBack Directory
[Name]

Cyclopropanecarboxylic acid, 1-[[[4-[[7-methoxy-6-(sulfooxy)-4-quinolinyl]oxy]phenyl]amino]carbonyl]-
[CAS]

1628530-37-9
[Synonyms]

Cabozantinib Metabolite M2a
Cabozantinib Des-O-fluoroanile-6’-Sulfate
Cyclopropanecarboxylic acid, 1-[[[4-[[7-methoxy-6-(sulfooxy)-4-quinolinyl]oxy]phenyl]amino]carbonyl]-
[Molecular Formula]

C21H18N2O9S
[MOL File]

1628530-37-9.mol
[Molecular Weight]

474.44
Chemical PropertiesBack Directory
[density ]

1.633±0.06 g/cm3(Predicted)
[pka]

-6.22±0.18(Predicted)
Hazard InformationBack Directory
[Uses]

Cabozantinib Des-O-fluoroanile-6’-Sulfate is a metabolite of cabozantinib(C051500). Cabozantinib is a small molecule C-Met modulator. Cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell apoptosis.
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