| Identification | Back Directory | [Name]
Fingolimod Impurity 8 | [CAS]
162358-96-5 | [Synonyms]
Fingolimod Impurity 7
2-octylphenethyl iodide
1-?(2-?Iodoethyl)?-?2-?octylbenzene | [Molecular Formula]
C16H25I | [MOL File]
162358-96-5.mol | [Molecular Weight]
344.27 |
| Hazard Information | Back Directory | [Uses]
1-?(2-?Iodoethyl)?-?2-?octylbenzene is an impurity of Fingloimod (F805000), also known as FTY720. FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively). |
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Roark Standards
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Energy Chemical
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Pharma Affiliates
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