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ChemicalBook--->CAS DataBase List--->1621482-36-7

1621482-36-7

1621482-36-7 Structure

1621482-36-7 Structure
IdentificationBack Directory
[Name]

LOLJEILMPWPILA-WZDCOHRSSA-N
[CAS]

1621482-36-7
[Synonyms]

LOLJEILMPWPILA-WZDCOHRSSA-N
8-iso-15-keto Prostaglandin F2β
8-iso-15-keto Prostaglandin F2.beta.
9β,11α-dihydroxy-15-oxo-(8β)-prosta-5Z,13E-dien-1-oic acid
Prosta-5,13-dien-1-oic acid, 9,11-dihydroxy-15-oxo-, (5Z,8β,9β,11α,13E)-
[Molecular Formula]

C20H32O5
[MOL File]

1621482-36-7.mol
[Molecular Weight]

352.47
Chemical PropertiesBack Directory
[Boiling point ]

535.2±50.0 °C(Predicted)
[density ]

1.149±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
[pka]

4.76±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H360-H336
[Precautionary statements ]

P201-P202-P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

8-iso Prostaglandin F (8-iso PGF) is an isomer of PGF of non-enzymatic origin. It is one of 64 possible isomers of PGF which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF exhibits very weak contraction of human umbilical vein artery and does not promote aggregation of human whole blood. However, 8-iso PGF moderately contracts both the canine and porcine pulmonary vein, although the effect is much weaker than that exhibited by other isoprostanes such as 8-iso PGE1, 8-iso PGE2, or 8-iso PGF. 8-iso-15-keto PGF is a potential metabolite of 8-iso PGF via the 15-hydroxy PG dehydrogenase pathway. There are no published reports on the formation or biological activity of 8-iso-15-keto PGF.
[Definition]

ChEBI: 8-iso-15-keto Prostaglandin F2beta is a prostanoid.
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