Identification | Back Directory | [Name]
FENAMIDONE | [CAS]
161326-34-7 | [Synonyms]
REASON UTILIS FENOMEN FENAMIDONE RPA 407213 Fenamidone-[13C6] fenamidone (bsi,iso) Mepanipyrim, Pestanal Fenamidone@100 μg/mL in AcCN Fenamidone 100mg [161326-34-7] FenamidoneSolution,100mg/L,5x1ml Fenamidone@1000 μg/mL in Acetonitrile (5S)-3-anilino-5-methyl-2-methylsulfanyl-5-phenylimidazol-4-one (S)-1-ANILINO-4-METHYL-2-METHYLTHIO-4-PHENYL-2-IMIDAZOLIN-5-ONE (S)-4-Methyl-2-(methylthio)-4-phenyl-1-(phenylamino)-1H-imidazol-5(4H)-one 4H-Imidazol-4-one, 3,5-dihydro-5-methyl-2-(methylthio)-5-phenyl-3-(phenylamino)-, (5S)- fenamidone (ISO) (S)-5-methyl-2-methylthio-5-phenyl-3-phenylamino-3,5-dihydroimidazol-4-one | [Molecular Formula]
C17H17N3OS | [MDL Number]
MFCD03792823 | [MOL File]
161326-34-7.mol | [Molecular Weight]
311.4 |
Hazard Information | Back Directory | [Definition]
ChEBI: A member of the class of imidazolones that is 3,5-dihydroimidazol-4-one substituted at position 2 by a methylthiogroup, at position 3 by an anilino group and at position 5 by phenyl and methyl groups (the S-enantiomer). A fungicide effecti
e against Oomycete diseases such as downy mildew and certain leaf spot diseases. | [Uses]
Fungicide. | [Hazard]
Moderately toxic by ingestion and skin contact. Low toxicity by inhalation. | [Description]
Fenamidone (13; RPA 407213; (S)-5-methyl-2-methylthio-
5-phenyl-3-phenylamino-3,4-dihydroimidazol-4-one) is a complex III inhibitor
that does not derive from the strobilurins but rather
belongs to the imidazolinone chemical class. Fenamidone is a white woolly powder, with the
following characteristics: mp = 137 ?C; water solubility =
7.8 mg/L; logP = 2.8, and vp = 3.4×10?7 Pa. It was
first described by Mercer et al. (39) in 1998. Only the
S-enantiomer shows antifungal activity, thus offering a
reduction in application rates over the racemic mixture. | [Toxicity evaluation]
Fenamidone has an acute oral LD50 > 5,000 and an
acute dermal LD50 > 2,000 mg/kg in rats. Fenamidone is
not a skin or eye irritant, is negative in the Ames test, and
is nonteratogenic. It shows low toxicity to birds in acute
and dietary studies but has a 96-h fish LC50 of 0.74 mg/L. |
Safety Data | Back Directory | [Hazard Codes ]
N | [Risk Statements ]
50/53 | [Safety Statements ]
60-61 | [RIDADR ]
UN3077 9/PG 3 | [WGK Germany ]
2 | [Toxicity]
LD50 in male, female rats (mg/kg): >5000, 2028 orally; in rats (mg/kg): >2000 dermally; LC50 in bobwhite quail, mallard duck (mg/kg): >5200, >5200 dietary (Mercer) |
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Energy Chemical
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http://www.energy-chemical.com |
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