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ChemicalBook--->CAS DataBase List--->1611489-00-9

1611489-00-9

1611489-00-9 Structure

1611489-00-9 Structure
IdentificationBack Directory
[Name]

Benzyl-PEG8-THP
[CAS]

1611489-00-9
[Synonyms]

Benzyl-PEG8-THP
Benzyl-PEG9-THP
Benzyl-PEG7-THP
CAS_1611489-00-9
[Molecular Formula]

C28H48O10
[MDL Number]

MFCD29049395
[MOL File]

1611489-00-9.mol
[Molecular Weight]

544.67
Hazard InformationBack Directory
[Biological Activity]

Benzyl-PEG8-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
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