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ChemicalBook--->CAS DataBase List--->1607803-67-7

1607803-67-7

1607803-67-7 Structure

1607803-67-7 Structure
IdentificationBack Directory
[Name]

B I09
[CAS]

1607803-67-7
[Synonyms]

B I09
B I09,B I-09
7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one
5H-[1]Benzopyrano[3,4-c]pyridin-5-one, 7-(1,3-dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-
[Molecular Formula]

C16H17NO5
[MDL Number]

MFCD30742940
[MOL File]

1607803-67-7.mol
[Molecular Weight]

303.31
Chemical PropertiesBack Directory
[Boiling point ]

486.5±45.0 °C(Predicted)
[density ]

1.44±0.1 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[solubility ]

DMSO:11.75(Max Conc. mg/mL);38.74(Max Conc. mM)
[form ]

Solid
[pka]

8.50±0.20(Predicted)
[color ]

Yellow to brown
Hazard InformationBack Directory
[Uses]

B I09, is a novel chromenone-based covalent inhibitors of IIRE-1 RNase. It Inhibits IRE-1/XBP1 pathway, and thus growth of human chronic lymphocytic leukemia (CLL) cells in vitro and promotes CLL regression in a mouse model.
[storage]

4°C, protect from light
Spectrum DetailBack Directory
[Spectrum Detail]

B I09(1607803-67-7)1HNMR
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