| Identification | Back Directory | [Name]
(Z)-2-decanoic acid | [CAS]
15790-91-7 | [Synonyms]
(Z)-2-decanoic acid
(Z)-2-Decenoic acid
(Z)-dec-2-enoic acid
2-Decenoic acid, (2Z)-
cis-2-Decenoic acid >=95.0% (HPLC) | [Molecular Formula]
C10H18O2 | [MDL Number]
MFCD20543109 | [MOL File]
15790-91-7.mol | [Molecular Weight]
170.25 |
| Chemical Properties | Back Directory | [Boiling point ]
278.6±9.0 °C(Predicted) | [density ]
0.936 | [storage temp. ]
-20°C | [solubility ]
DMSO : 250 mg/mL (1468.43 mM; Need ultrasonic) | [form ]
Powder | [pka]
4.63±0.25(Predicted) | [color ]
Colorless to light yellow | [BRN ]
1721990 | [LogP]
3.715 (est) |
| Hazard Information | Back Directory | [Uses]
cis-2-Decenoic acid may be used to study its cytotoxic effect on the human HepG2 cell line. It has also been used to study its synergistic anti-spirochetal effect. | [Uses]
cis-2-Decenoic Acid is an organic compound which appears to be functionally and structurally related to the class of short-chain fatty acid signaling molecules such as diffusible signal factor, which act as cell-to-cell communication molecules in bacteria and fungi. | [Definition]
ChEBI: Cis-2-decenoic acid is a 2-decenoic acid having its double bond in the cis configuration. | [Biochem/physiol Actions]
cis-2-Decenoic acid is a fatty acid messenger (signaling molecule) produced by Pseudomonas aeruginosa. It possesses anti-biofilm property and converts most of the cells to planktonic (free-swimming) phenotype. cis-2-Decenoic acid retains the susceptibility of the bacteria towards antimicrobial agents. It does not exhibit any toxicity towards human cells and thus, might be used for treating biofilm-associated infections. cis-2-Decenoic acid is considered active even in nano-molar ranges. It mediates the transition of dormant P. aeruginosa and Escherichia coli to their biologically active state without affecting the number of cells. cis-2-Decenoic acid is effective against E. coli and Klebsiella pneumoniae mixed-species biofilms when used along with antimicrobial agents. | [storage]
Store at -20°C |
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