| Identification | Back Directory | [Name]
Glycine, N,N'-1,4-naphthalenediylbis[N-[(4-methoxyphenyl)sulfonyl]- | [CAS]
1567836-15-0 | [Synonyms]
CPUY192018
CPUY192018 Na2
CPUY192018disodium
CPUY192018-disodium
CPUY192018 Disodium
Glycine, N,N'-1,4-naphthalenediylbis[N-[(4-methoxyphenyl)sulfonyl]- | [Molecular Formula]
C28H26N2O10S2 | [MOL File]
1567836-15-0.mol | [Molecular Weight]
614.64 |
| Chemical Properties | Back Directory | [Boiling point ]
881.9±75.0 °C(Predicted) | [density ]
1.502±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
3.10±0.30(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
CPUY192018 Disodium is a potent small-molecule inhibitor of the Keap1-Nrf2 PPI. CPUY192018 Disodium has a cytoprotective effect against DSS in both NCM460 cells and mouse colon via the activation of Nrf2 signaling. Activation of Nrf2 by directly inhibiting the Keap1-Nrf2 PPI may be beneficial as a treatment for ulcerative colitis. |
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