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ChemicalBook--->CAS DataBase List--->1532533-78-0

1532533-78-0

1532533-78-0 Structure

1532533-78-0 Structure
IdentificationBack Directory
[Name]

TGR-1202 (hydrochloride)
[CAS]

1532533-78-0
[Synonyms]

Umbralisib HCl
RP5264 hydrochloride
RP-5264 hydrochloride
RP 5264 hydrochloride
Umbralisib hydrochloride
TGR-1202 (hydrochloride)
Umbralisib (TGR-1202) HCl
TGR-1202 hydrochloride(Umbralisib)
Umbralisib (TGR-1202) hydrochloride
RP5264 HYDROCHLORIDE; TGR1202 HYDROCHLORIDE; TGR 1202 HYDROCHLORIDE; RP-5264 HYDROCHLORIDE; RP 5264 HYDROCHLORIDE
[Molecular Formula]

C31H25ClF3N5O3
[MOL File]

1532533-78-0.mol
[Molecular Weight]

608.02
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO: ≥ 150 mg/mL (246.71 mM); Water: < 0.1 mg/mL (insoluble)
[form ]

Solid
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

2-?[(1S)?-?1-?[4-?Amino-?3-?[3-?fluoro-?4-?(1-?methylethoxy)?phenyl]?-?1H-?pyrazolo[3,?4-?d]?pyrimidin-?1-?yl]?ethyl]?-?6-?fluoro-?3-?(3-?fluorophenyl)?-4H-?1-?benzopyran-?4-?one Hydrochloride (1:1) is a drug candidate. It is used in the preparation of 1H-Pyrazolo[3,4-d]pyrimidine derivatives as selective PI3K delta inhibitors for treatment of autoimmune and inflammatory disorders, and proliferative diseases such as cancer.
[storage]

Store at -20°C
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