| Identification | Back Directory | [Name]
FL118 | [CAS]
151636-76-9 | [Synonyms]
FL118
CS-1718
10,11-(methylenedioxy)-(20R)-camptothecin
10H-1,3-Dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7R)- | [Molecular Formula]
C21H16N2O6 | [MOL File]
151636-76-9.mol | [Molecular Weight]
392.36 |
| Chemical Properties | Back Directory | [Boiling point ]
812.1±65.0 °C(Predicted) | [density ]
1?+-.0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 2.7 mg/mL (6.88 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [pka]
11.18±0.20(Predicted) | [color ]
Off-white to yellow |
| Hazard Information | Back Directory | [Uses]
(R)-FL-118 is a derivative of Camptothecin (C175150), which is antitumor alkaloid that binds to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I, trapping the enzyme in a covalent linkage with DNA. | [storage]
Store at -20°C |
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| Company Name: |
SPIRO PHARMA
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| Tel: |
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| Website: |
www.spiropharma.com.cn |
| Company Name: |
Cckinase, Inc.
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+1 (732)236-3202 |
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www.cckinase.com |
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Energy Chemical
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http://www.energy-chemical.com |
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Wuhan Topule
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http://www.topule.com/ |
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