| Identification | Back Directory | [Name]
Strictosidinic acid | [CAS]
150148-81-5 | [Synonyms]
Strictosidinic acid
(2S,3R,4S)-3-Ethenyl-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-4-[[(1S)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-2H-pyran-5-carboxylic acid
2H-Pyran-5-carboxylic acid, 3-ethenyl-2-(β-D-glucopyranosyloxy)-3,4-dihydro-4-[[(1S)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl]-, (2S,3R,4S)- | [Molecular Formula]
C26H32N2O9 | [MDL Number]
MFCD18072307 | [MOL File]
150148-81-5.mol | [Molecular Weight]
516.54 |
| Chemical Properties | Back Directory | [Boiling point ]
792.8±60.0 °C(Predicted) | [density ]
1.50±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, stored under nitrogen | [form ]
Solid | [pka]
4.67±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
Strictosidinic acid, an glycosidic indole monoterpene alkaloid isolated from the leaves of Psychotria myriantha, inhibits the precursor enzymes of 5-HT biosynthesis and reduces 5-HT content. It has peripheral analgesic and antipyretic activity in mice. | [in vivo]
Strictosidinic acid (20 μg/μl; intra-hippocampal injection) causes a significance of 83.5% reduction in 5-HT levels. Strictosidinic acid (10 mg/kg; ip) causes a 63.4% reduction in 5- HT levels and a 67.4% reduction in DOPAC values in male Wistar rats, weighing 200-250 g. | [target]
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