| Identification | Back Directory | [Name]
glybuzole | [CAS]
1492-02-0 | [Synonyms]
621 YT
AN1324
RP7891
1395 TH
Gludiase
Glybzole
glybuzole
Glybuzolum
Desaglybuzole
Sulfamidothiodiazol
N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
BENZENESULPHONAMIDE,N-(5-TERT-BUTYL-1,3,4-THIADIAZOL-2-YL)- | [EINECS(EC#)]
216-081-2 | [Molecular Formula]
C12H15N3O2S2 | [MDL Number]
MFCD00724711 | [MOL File]
1492-02-0.mol | [Molecular Weight]
297.401 |
| Hazard Information | Back Directory | [Originator]
Gludease,Kyowa Hakko,Japan,1972 | [Definition]
ChEBI: Glybuzole is an organic molecular entity. | [Manufacturing Process]
15.7 g of 2-amino-5-tert-butyl-1,3,4-thiadiazole (0.1 mol) and 17.6 g of
benzene sulfonyl chloride (0.1 mol) were dissolved in 150 ml dry pyridine and
heated over steam for 4 hr. The pyridine was removed by distillation under
reduced pressure and the residue treated with 50 ml 2N HCl. The solid
product, MP 162° to 163°C. was filtered off and recrystallized once from
benzene and twice from 50% aqueous EtOH. | [Therapeutic Function]
Oral hypoglycemic |
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