Identification | Back Directory | [Name]
5'-O-(4,4'-DIMETHOXYTRITYL)-2'-FLUORO-D-URIDINE | [CAS]
146954-74-7 | [Synonyms]
DMT-2'-F-U DMT-2'-F-dU 5'-DMT-2'-F-dU 5'-O-DMT-2'-F-dU 1-((2R,3R,4R,5R) -5-((Bis(4-methoxyphenyl) 2'-Deoxy-5'-O-DMT-2'-fluorouridine 5'-O-DMT-2'-Fluoro-2'-deoxyuridine 2'-Deoxy-5'-O-DMTr-2'-fluoro-uridine 2'-Deoxy-5'-O-DMT-2'-fluoro-D-uridine -3-fluoro-4-hydroxytetrahydrofuran-2-yl) 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-FLUORO-D-URIDINE 5'-O-(4,4'-DiMethoxytrityl)-2'-fluoro-2'-deoxyuridine 2’-Deoxy-5’-O-(4,4’-dimethoxytrityl)-2’-fluorouridine 5'-O-(4,4'-DIMETHOXYTRITYL)-2'-FLUORO-D-URIDINE USP/EP/BP 5'-O-(4,4'-Dimethoxytrityl)-2'-fluoro-2'-deoxyuridine, 98%, 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-2'-fluorouridine Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro- 1-(5-{[BIS(4-METHOXYPHENYL)(PHENYL)METHOXY]METHYL}-3-FLUORO-4-HYDROXYOXOLAN-2-YL)-3H-PYRIMIDINE-2,4- 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-fluoro-4-hydroxyoxolan-2-yl]pyrimidine-2,4-dione 1-((2R,3R,4R,5R)-5-((Bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione | [EINECS(EC#)]
2017-001-1 | [Molecular Formula]
C30H29FN2O7 | [MDL Number]
MFCD06657648 | [MOL File]
146954-74-7.mol | [Molecular Weight]
548.56 |
Chemical Properties | Back Directory | [density ]
1.38±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
Powder | [pka]
9.39±0.10(Predicted) | [color ]
White to Pale Yellow | [InChIKey]
CSSFZSSZXOCCJB-MNBKXICWNA-N | [SMILES]
N1(C=CC(=O)NC1=O)[C@@H]1O[C@H](COC(C2=CC=CC=C2)(C2=CC=C(C=C2)OC)C2=CC=C(C=C2)OC)[C@@H](O)[C@H]1F |&1:8,10,36,38,r| |
Hazard Information | Back Directory | [Definition]
2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5’-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity. | [Biological Activity]
2'-Deoxy-5'-O-DMT-2'-fluorouridine (compound 15h) has 100% inhibition against YFV at 20 mM. 2'-Deoxy-5'-O-DMT-2'-fluorouridine proves to be noncytotoxic at concentrations up to 20 mM.
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