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ChemicalBook--->CAS DataBase List--->146135-18-4

146135-18-4

146135-18-4 Structure

146135-18-4 Structure
IdentificationBack Directory
[Name]

CarbaMic acid, (1-Methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl)-, phenylMethyl ester (9CI)
[CAS]

146135-18-4
[Synonyms]

TUWDLUFFAHHNEF-UHFFFAOYSA-N
Carbamic acid, N-(1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl)-, phenylmethyl ester
CarbaMic acid, (1-Methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl)-, phenylMethyl ester (9CI)
[Molecular Formula]

C25H21N5O2
[MDL Number]

MFCD19443120
[MOL File]

146135-18-4.mol
[Molecular Weight]

423.47
Hazard InformationBack Directory
[Description]

GW841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomains. GW841819X displayed activity in vivo against NUT-midline carcinoma, multiple myeloma, mixed-lineage leukemia, and acute myeloid leukemia. Bromodomain and extra-terminal (BET) proteins belong to a class of proteins collectively called epigenetic "readers". BET bromodomains have emerged as promising drug targets for treatment of cancers, inflammatory diseases, and other medical conditions.
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