| Identification | Back Directory | [Name]
1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE | [CAS]
145645-62-1 | [Synonyms]
NO-711
NNC 711
NNC711,HCl
NO-711 HYDROCHLORIDE
NNC-711 hydrochloride
YZYRTEYMUTWJPL-UHFFFAOYSA-N
NO-711 HCL POTENT GABA UPTAKE IN
1,2,5,6-Tetrahydro-1-(2-(((diphenylmethylene)amino)oxy]ethyl)-3-pyridinecarboxylicacidhydrochloride
1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
1-[2-[[(diphenylmethylene)imino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride
1-(2-(((DIPHENYLMETHYLENE)IMINO)OXY)ETHYL)-1,2,5,6-TETRAHYDRO-3-PYRIDINE CARBOXYLIC ACID HYDROCHLORIDE
1-[2-[[(Diphenylmethylene)imino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride hydrochloride | [Molecular Formula]
C21H23ClN2O3 | [MDL Number]
MFCD00153853 | [MOL File]
145645-62-1.mol | [Molecular Weight]
386.87 |
| Hazard Information | Back Directory | [Uses]
NNC 711 is an anticonvulsant agent and a selective GABA uptake inhibitor (1,2). | [Uses]
NO-711 hydrochloride is suitable for use as γ-aminobutyric acid (GABA) transporter-1 (GAT-1) antagonists or GABA uptake inhibitor. | [Biological Activity]
Potent and selective inhibitor of GABA uptake by GAT-1 (IC 50 values are 0.04, 171, 1700 and 622 μ M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Anticonvulsant following systemic administration in vivo . | [Biochem/physiol Actions]
NO-711 is a potent and selective GABA uptake inhibitor that crosses the blood-brain barrier. | [storage]
Desiccate at +4°C |
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