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ChemicalBook--->CAS DataBase List--->144678-63-7

144678-63-7

144678-63-7 Structure

144678-63-7 Structure
IdentificationBack Directory
[Name]

N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanyl-(2S)-2-hydroxy-3-methylbutanoic acid hydrate
[CAS]

144678-63-7
[Synonyms]

NSC 668036
NSC 668036 hydrate
NSC668036,NSC 668036
N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanine-(1S)-1-carboxy-2-methylpropyl ester
N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-Alanine-(1S)-1-carboxy-2-methylpropyl ester hydrate
N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-(2S)-2-hydroxy-3-methylbutanoyl-L-alanyl-(2S)-2-hydroxy-3-methylbutanoic acid hydrate
[Molecular Formula]

C21H36N2O9
[MDL Number]

MFCD30536365
[MOL File]

144678-63-7.mol
[Molecular Weight]

460.52
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

H2O: ≥5mg/mL
[form ]

powder
[color ]

white to tan
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

NSC 668036 hydrate may be used in Wnt-mediated cell signaling studies.
[Biochem/physiol Actions]

NSC 668036 binds to the PDZ domain of the Wnt-pathway signaling molecule Disheveled (Dvl), blocking the binding and activation of Dvl by Frizzled. In Xenopus embryos, NSC 668036 inhibited Wnt3A-induced expression of the target gene Siamois and formation of secondary axes.
[storage]

Store at -20°C
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