| Identification | Back Directory | [Name]
Voxelotor | [CAS]
1446321-46-5 | [Synonyms]
GTx011
GBT 440
Voxelotor
GBT-440(Voxelotor)
GTX011;GTX011;GTX011
Hemoglobin Modulators-1
Voxelotor(GBT440, GTX011)
Voxelotor, GBT-440, GBT 440, GBT440, GTx-011, GTx011, GTx 011
VOXELOTOR, GBT-440, GBT 440, GBT440, GTX-011, GTX011, GTX 011;
2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
2-Hydroxy-6-{[2-(1-isopropyl-1H-pyrazol-5-yl)-3-pyridinyl]methoxy}benzaldehyde
2-hydroxy-6-([2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl]methoxy)benzaldehyde
Benzaldehyde, 2-hydroxy-6-[[2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-3-pyridinyl]methoxy]- | [Molecular Formula]
C19H19N3O3 | [MDL Number]
MFCD29053764 | [MOL File]
1446321-46-5.mol | [Molecular Weight]
337.37 |
| Chemical Properties | Back Directory | [Melting point ]
95 - 97oC | [Boiling point ]
539.2±50.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
7.67±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
GBT 440 is a potent allosteric effector of sickle cell hemoglobin (Hb) that increases the affinity of Hb for oxygen and inhibits its polymerization when subjected to hypoxic conditions. |
|
|