| Identification | Back Directory | [Name]
IRL-1038 | [CAS]
144602-02-8 | [Synonyms]
IRL-1038
IRL-1038, HUMAN
ENDOTHELIN-1 (11-21)
ENDOTHELIN-1 (11-21), HUMAN
M.W. 1409.70 C68H94N14O15S2
Endothelin-1 (11-21)
IRL-1038
[CYS11, CYS15]ENDOTHELIN-I (11-21)
[CYS11-CYS15]-ENDOTHELIN-1 (11-21)
Endothelin-1 (11-21) trifluoroacetate salt
CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP
H-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-OH
11-21-Endothelin 1 (swine reduced), cyclic (11→15)-disulfide
CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP (DISULFIDE BRIDGE CYS1-CYS5)
Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp (Disulfide bridge Cys11-Cys15) | [Molecular Formula]
C68H92N14O15S2 | [MDL Number]
MFCD00214658 | [MOL File]
144602-02-8.mol | [Molecular Weight]
1409.67 |
| Hazard Information | Back Directory | [Uses]
IRL 1038 is an endothelin B receptor selective antagonist with a Ki of 6-11 nM[1]. | [storage]
Desiccate at -20°C | [References]
[1] Urade Y, et al. An endothelin B receptor-selective antagonist: IRL 1038, [Cys11-Cys15]-endothelin-1(11-21). FEBS Lett. 1992 Oct 12;311(1):12-6. doi: 10.1016/0014-5793(92)81355-p. DOI:10.1016/0014-5793(92)81355-p |
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