| Identification | Back Directory | [Name]
YM 26734 | [CAS]
144337-18-8 | [Synonyms]
YM 26734
4-(3,5-Didodecanoyl-2,4,6-trihydroxyphenyl)-7-hydroxy-2-(4-hydroxyphenyl)chroman
1-[3-dodecanoyl-2,4,6-trihydroxy-5-[7-hydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]phenyl]dodecan-1-one
1,1'-[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis-1-dodecanone
1-Dodecanone, 1,1'-(5-(3,4-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl)-2,4,6-trihydroxy-1,3-phenylene)bis- | [Molecular Formula]
C45H62O8 | [MDL Number]
MFCD00918068 | [MOL File]
144337-18-8.mol | [Molecular Weight]
730.97 |
| Hazard Information | Back Directory | [Uses]
YM-26734 is a derivative of a compound isolated from the fruit of H. amygdaline that competitively inhibits rabbit platelet sPLA2 which is a diverse family of low molecular weight PLA2s with tissue-specific expression patterns and actions. | [Biological Activity]
Competitive inhibitor of secretory phospholipase A 2 (sPLA 2 ) that exhibits a broad inhibitory profile to several sPLA 2 s (IC 50 values are 0.2, 1, 1, 1 and 3 μ M for sPLA 2 -X, -IIA, -IID, -V and -IIE respectively). Displays minimal activity at sPLA 2 -IIF and no activity at cytosolic PLA 2 , cyclooxygenase and lipoxygenase. Ameliorates local inflammatory responses in TPA-induced mouse ear edema. | [storage]
Store at -20°C |
|
| Company Name: |
Lynnchem
|
| Tel: |
86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
| Company Name: |
Novachemistry
|
| Tel: |
44-20819178-90 02081917890 |
| Website: |
https://www.novachemistry.com/ |
|