| Identification | Back Directory | [Name]
4-(4,4-DiMethyl-2,5-dioxoiMidazolidin-1-yl)-2-trifluoroMethylbenzonitrile | [CAS]
143782-20-1 | [Synonyms]
185807
RU 56279
4-(4,4-DIMETHYL-2,5-DIOXOIMIDAZOLIDIN-1-YL)-2-TRIFLUOROMETHYLBENZONITRILE
2-(trifluoromethyl)-4-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)benzonitrile
4-(4,4-Dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile
Benzonitrile, 4-(4,4-diMethyl-2,5-dioxo-1-iMidazolidinyl)-2-(trifluoroMethyl)- | [Molecular Formula]
C13H10F3N3O2 | [MDL Number]
MFCD19689673 | [MOL File]
143782-20-1.mol | [Molecular Weight]
297.23 |
| Hazard Information | Back Directory | [Uses]
4-(4,4-Dimethyl-2,5-dioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile is an intermediate in the synthesis of Oxo-MDV 3100 (Oxo-enzalutamide) (O857800), which is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer. |
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