Identification | Back Directory | [Name]
GYKI 53405 | [CAS]
143691-37-6 | [Synonyms]
LY 293606 GYKI 53405 1-[5-(4-aminophenyl)-8-methyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepin-7-yl]ethanone Ethanone, 1-[5-(4-aminophenyl)-8,9-dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-7-yl]- | [Molecular Formula]
C19H19N3O3 | [MDL Number]
MFCD09475604 | [MOL File]
143691-37-6.mol | [Molecular Weight]
337.37 |
Hazard Information | Back Directory | [Description]
GYKI-53405, also known as LY 293606, is a noncompetitive AMPA receptor antagonist. GYKI-53405 binds specifically to Xenopus brain membranes with KD and Bmax values of 4.5 microM and 35 pmol mg-1 protein respectively. Binding is increased in the presence of Mg2+ and is unaffected by AMPA or kainate. |
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BOC Sciences
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16314854226 |
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www.bocsci.com |
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