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ChemicalBook--->CAS DataBase List--->143142-90-9

143142-90-9

143142-90-9 Structure

143142-90-9 Structure
IdentificationBack Directory
[Name]

R-(+)-2-TRIFLUOROMETHYLOXIRANE
[CAS]

143142-90-9
[Synonyms]

R-(+)-2-TRIFLUOROMETHYLOXIRANE
(2R)-2-(trifluoromethyl)oxirane
R-(+)-2-TRIFLUOROMETHYLOXIRANE, 97
Oxirane, 2-(trifluoromethyl)-, (2R)-
(2R)-2-(Trifluoromethyl)oxirane (ee)
(2R)-(+)-3,3,3-Trifluoro-1,2-propenoxide
(2R)-2-(Trifluoromethyl)oxirane, (2R)-1,2-Epoxy-3,3,3-trifluoropropane
[Molecular Formula]

C3H3F3O
[MDL Number]

MFCD08276876
[MOL File]

143142-90-9.mol
[Molecular Weight]

112.05
Chemical PropertiesBack Directory
[Boiling point ]

25-32 °C
[density ]

1.294 g/mL at 25 °C
[refractive index ]

n20/D <1.300
[Fp ]

-15 °F
[storage temp. ]

2-8°C
Safety DataBack Directory
[Hazard Codes ]

F+
[Risk Statements ]

12
[Safety Statements ]

3
[RIDADR ]

UN 1993 3/PG 1
[WGK Germany ]

3
[HS Code ]

2910900090
Hazard InformationBack Directory
[Uses]

(R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane can be used as a substrate to synthesize:
  • Substituted trifluoro amino propanols, which are found to be potent inhibitors of cholesteryl ester transfer protein.
  • (2R) Trifluoro-(methoxybenzyloxy)-propanol (chiral glycol) by reacting with 4-methoxybenzyl alcohol in the presence of NaH. Chiral glycol intermediate is further utilized for the preparation of trifluoromethyl glycol carbamates as potential monoacylglycerol lipase (MAGL) inhibitors.

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