Identification | Back Directory | [Name]
1H-Pyrrole-3-carboxylic acid, 5-[[2,5-dimethyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-3-yl]methylene]-4,5-dihydro-2-methyl-4-oxo-, ethyl ester, (5E)- | [CAS]
1428183-45-2 | [Synonyms]
TDR32570 TDR-32570 TDR 32570 GNFPf1753 GNF-Pf-1753 GNF Pf 1753 1H-Pyrrole-3-carboxylic acid, 5-[[2,5-dimethyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-3-yl]methylene]-4,5-dihydro-2-methyl-4-oxo-, ethyl ester, (5E)- | [Molecular Formula]
C22H21F3N2O3 | [MOL File]
1428183-45-2.mol | [Molecular Weight]
418.41 |
Hazard Information | Back Directory | [Description]
TDR32570 is an antimalarial agent. | [Uses]
TDR 32750 is an antimalarial agent. TDR 32750 inhibits P. falciparum activity with an ED50 value of 0.014 μM[1]. | [References]
[1] Dinakaran Murugesan, et al. Structure-activity relationship studies of pyrrolone antimalarial agents. ChemMedChem. 2013 Sep;8(9):1537-44. DOI:10.1002/cmdc.201300177 |
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