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ChemicalBook--->CAS DataBase List--->1428183-45-2

1428183-45-2

1428183-45-2 Structure

1428183-45-2 Structure
IdentificationBack Directory
[Name]

1H-Pyrrole-3-carboxylic acid, 5-[[2,5-dimethyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-3-yl]methylene]-4,5-dihydro-2-methyl-4-oxo-, ethyl ester, (5E)-
[CAS]

1428183-45-2
[Synonyms]

TDR32570
TDR-32570
TDR 32570
GNFPf1753
GNF-Pf-1753
GNF Pf 1753
1H-Pyrrole-3-carboxylic acid, 5-[[2,5-dimethyl-1-[2-(trifluoromethyl)phenyl]-1H-pyrrol-3-yl]methylene]-4,5-dihydro-2-methyl-4-oxo-, ethyl ester, (5E)-
[Molecular Formula]

C22H21F3N2O3
[MOL File]

1428183-45-2.mol
[Molecular Weight]

418.41
Chemical PropertiesBack Directory
[Boiling point ]

552.6±50.0 °C(Predicted)
[density ]

1.27±0.1 g/cm3(Predicted)
[pka]

-1.76±0.60(Predicted)
Hazard InformationBack Directory
[Description]

TDR32570 is an antimalarial agent.
[Uses]

TDR 32750 is an antimalarial agent. TDR 32750 inhibits P. falciparum activity with an ED50 value of 0.014 μM[1].
[References]

[1] Dinakaran Murugesan, et al. Structure-activity relationship studies of pyrrolone antimalarial agents. ChemMedChem. 2013 Sep;8(9):1537-44. DOI:10.1002/cmdc.201300177
1428183-45-2 suppliers list
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