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ChemicalBook--->CAS DataBase List--->142715-48-8

142715-48-8

142715-48-8 Structure

142715-48-8 Structure
IdentificationBack Directory
[Name]

4-(3,4-Dihydro-6,7-diMethoxy-2(1H)-isoquinolinyl)-N-[2-(3,4-diMethoxyphenyl)ethyl]-6,7-diMethoxy-2-quinazolinaMine Monohydrochloride
[CAS]

142715-48-8
[Synonyms]

CP-100356 Monohydrochloride
4-(3,4-Dihydro-6,7-diMethoxy-2(1H)-isoquinolinyl)-N-[2-(3,4-diMethoxyphenyl)ethyl]-6,7-diMethoxy-2-quinazolinaMine Monohydrochloride
[Molecular Formula]

C31H37ClN4O6
[MDL Number]

MFCD00911858
[MOL File]

142715-48-8.mol
[Molecular Weight]

597.102
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: >5mg/mL
[form ]

powder
[color ]

white to off-white
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Chemical Properties]

Off-White to Light Tan Solid
[Uses]

CP-100356 is a specific inhibitor of MDR1 (P-Gp), the protypical ABC transporter. CP-100356 also inhibits prazosin transport in human breast cancer resistance protein (BCRP)-transfected MDCKII cells, suggesting that it acts as a dual inhibitor. CP-100356 does not inhibit multidrug resistance-associated protein 2 (MPR2 IC50 >15 mM).
[storage]

Desiccate at RT
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