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ChemicalBook--->CAS DataBase List--->1426916-00-8

1426916-00-8

1426916-00-8 Structure

1426916-00-8 Structure
IdentificationBack Directory
[Name]

ML-299
[CAS]

1426916-00-8
[Synonyms]

ML-299
4-bromo-N-[(2S)-1-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]decan-8-yl]propan-2-yl]benzamide
Benzamide, 4-bromo-N-[(1S)-2-[1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro[4.5]dec-8-yl]-1-methylethyl]-
[Molecular Formula]

C23H26BrFN4O2
[MDL Number]

MFCD31618426
[MOL File]

1426916-00-8.mol
[Molecular Weight]

489.38
Chemical PropertiesBack Directory
[Boiling point ]

708.8±60.0 °C(Predicted)
[density ]

1.47±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:20): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 1 mg/ml
[form ]

A crystalline solid
[pka]

14.02±0.46(Predicted)
Hazard InformationBack Directory
[Uses]

ML-299 is a dual inhibitor of the two mammalian forms of phospholipase D (PLD), PLD1 and PLD2. It dose-dependently decreases the invasive migration of U87-MG glioblastoma cells into matrigel.
[storage]

Store at -20°C
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