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ChemicalBook--->CAS DataBase List--->141992-47-4

141992-47-4

141992-47-4 Structure

141992-47-4 Structure
IdentificationBack Directory
[Name]

NSC 625987
[CAS]

141992-47-4
[Synonyms]

9(10H)-Acridinethione,1,4-dimethoxy-
[Molecular Formula]

C15H13NO2S
[MDL Number]

MFCD08276925
[MOL File]

141992-47-4.mol
[Molecular Weight]

271.33
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

DMSO: 14 mg/mL
[form ]

Powder
[color ]

Brown to khaki
Safety DataBack Directory
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

NSC 625987 is a cyclin-dependent kinase (cdk) 4 inhibitor.
[Definition]

ChEBI: 1,4-dimethoxy-10H-acridine-9-thione is a member of acridines.
[Biological Activity]

Cyclin-dependent kinase (cdk) 4 inhibitor (IC 50 = 0.2 μ M at cdk4/cyclin D1). Displays > 500-fold selectivity over cdk2 (IC 50 > 100 μ M for cdc2/cyclin A, cdk2/cyclin A and cdk2/cyclin E).
[storage]

Store at -20°C
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