Identification | Back Directory | [Name]
N-cis-octadec-9Z-enoyl-L-Homoserine lactone Exclusive | [CAS]
1400974-23-3 | [Synonyms]
N-cis-octadec-9-enoyl-L-Homoserine lactone (Z)-N-[(3S)-2-oxooxolan-3-yl]octadec-9-enamide N-cis-octadec-9Z-enoyl-L-Homoserine lactone Exclusive | [Molecular Formula]
C22H39NO3 | [MOL File]
1400974-23-3.mol | [Molecular Weight]
365.55 |
Hazard Information | Back Directory | [Description]
Quorum sensing is a regulatory process used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group) and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. C18:1-Δ9 cis-(L)-HSL is a long-chain AHL that may have antimicrobial activity and thus, might be used to inhibit pathogenesis by regulating bacerial quorum sensing signaling. | [storage]
Store at -20°C |
|
|