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ChemicalBook--->CAS DataBase List--->139886-32-1

139886-32-1

139886-32-1 Structure

139886-32-1 Structure
IdentificationBack Directory
[Name]

Milameline
[CAS]

139886-32-1
[Synonyms]

Milameline
CI-979|||CI-979
Milameline [inn]
RU35926|||RU35926
Milameline hydrochloride
(E)-1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxaldehyde o-methyloxime
3-Pyridinecarboxaldehyde, 1,2,5,6-tetrahydro-1-methyl-, o-methyloxime, (E)-
3-Pyridinecarboxaldehyde, 1,2,5,6-tetrahydro-1-methyl-, O-methyloxime, [C(E)]-
(E)-1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxaldehydeO-methyloximehydrochloride
[Molecular Formula]

C8H14N2O
[MDL Number]

MFCD00864175
[MOL File]

139886-32-1.mol
[Molecular Weight]

154.212
Chemical PropertiesBack Directory
[Boiling point ]

221.1±50.0 °C(Predicted)
[density ]

1.00±0.1 g/cm3(Predicted)
[storage temp. ]

Desiccate at -20°C
[pka]

8.22±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

Antidementia (partial muscarinic agonist.
[Uses]

Milameline is a muscarinic receptor agonist.
[Biological Activity]

Muscarinic receptor agonist that displays roughly equal affinity at all receptor subtypes (K i values are 2.3, 2.4, 3.6, 3.8 and 4.3 μ M for hM 1 , hM 2 , hM 3 , hM 4 and hM 5 receptors respectively). Cognitive enhancer; reverses spatial memory deficits in rats.
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