Identification | Back Directory | [Name]
RY796 | [CAS]
1393441-53-6 | [Synonyms]
RY796 2-(DIMETHYLAMINO)-5-[(2-METHYL-1-OXOPROPYL)AMINO]-N-[(1R)-1-PHENYLETHYL]-BENZAMIDE | [Molecular Formula]
C21H27N3O2 | [MDL Number]
MFCD28160786 | [MOL File]
1393441-53-6.mol | [Molecular Weight]
353.46 |
Chemical Properties | Back Directory | [Boiling point ]
561.0±50.0 °C(Predicted) | [density ]
1.132±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [form ]
Solid | [pka]
13.95±0.46(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Biological Activity]
RY796 is a potent and selective voltage-gated potassium (KV2) channel inhibitor with IC50s of 0.25 μM and 0.09 μM for KV2.1 and KV2.2. RY796 has analgesic activity[1]. | [References]
[1]. Herrington J, et al. Identification of novel and selective Kv2 channel inhibitors. Mol Pharmacol. 2011 Dec;80(6):959-64. |
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