| Identification | Back Directory | [Name]
Hydroxy-PEG3-Mes | [CAS]
139115-89-2 | [Synonyms]
Ms-peg4
CAS_139115-89-2
Hydroxy-PEG3-MS
Hydroxy-PEG3-Mes | [Molecular Formula]
C7H16O6S | [MDL Number]
MFCD22574814 | [MOL File]
139115-89-2.mol | [Molecular Weight]
228.26 |
| Chemical Properties | Back Directory | [Boiling point ]
398.2±27.0 °C(Predicted) | [density ]
1.256±0.06 g/cm3(Predicted) | [form ]
Liquid | [pka]
14.36±0.10(Predicted) | [color ]
Colorless to light yellow |
| Hazard Information | Back Directory | [Biological Activity]
Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | [References]
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Wuhan Topule
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+86-02787215551 +86-19945035818 |
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http://www.topule.com/ |
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