| Identification | Back Directory | [Synonyms]
PF-4800567 HCl
PF-4800567 hydrochloride >=98% (HPLC)
3-[(3-chlorophenoxy)methyl]-1-(oxan-4-yl)pyrazolo[3,4-d]pyrimidin-4-amine:hydrochloride | [MDL Number]
MFCD20926348 |
| Hazard Information | Back Directory | [Biological Activity]
PF-4800567 is a casein kinase 1e (CK1e) selective inhibitor (IC50 = 32 nM) th at is 20 fold selective for the CK1e isoform over CK1d. PF-4800567 blockes CK1e-mediated PER3 nuclear translocationbut does not effect the circadian clock in animal studies.''PF-4800567 is also known as (3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine hydrochloride). It can block the epidermal growth factor receptor (EGFR) at micromolar concentrations. PF-4800567 helps to improve the locomotor stimulant reaction to methamphetamine (MA) and fentanyl. | [storage]
Desiccate at RT |
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| Company Name: |
BOC Sciences
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| Tel: |
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| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
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| Tel: |
4008-099-669 |
| Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList112975/0.htm |
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