| Identification | Back Directory | [Name]
CYCLO(ARG-GLY-ASP-D-PHE-VAL) | [CAS]
137813-35-5 | [Synonyms]
cRGDfV
EMD 66203
CYCLO(RGDD-FV)
EMD 66203, c(RGDfV)
RGDFV PEPTIDE, CYCLIC
Cyclo(Arg-Gls-Asp-D-Phe-Val)
CYCLO(ARG-GLY-ASP-D-PHE-VAL)
Cyclo(-Arg-Gly-Asp-D-Phe-Val) trifluoroacetate salt
Cyclo(L-arginylglycyl-L-α-aspartyl-D-phenylalanyl-L-valyl)
Cyclo(Arg-Gly-Asp-D-Phe-Val) - CAS 137813-35-5 - Calbiochem | [Molecular Formula]
C26H38N8O7 | [MDL Number]
MFCD00274410 | [MOL File]
137813-35-5.mol | [Molecular Weight]
574.63 |
| Hazard Information | Back Directory | [General Description]
Potent inhibitor of cell adhesion. Inhibits tumor cell adhesion to laminin and vitronectin substrates. In vivo investigations in rats showed it to be useful in the amelioration of ischemic acute renal failure in rats. Also inhibits tubular obstruction by preventing cell-cell adhesion. Inhibits the redistribution of c-Src into focal adhesions, thereby leading to impaired MAP Kinase activation. | [Biochem/physiol Actions]
Primary Targetinhibits tumor cell adhesion to laminin and vitronectin substrates |
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